Retrotransposons, also generally termed Mobile Elements (MEs), constitute ~50% of the human genome with millions of copies classified into the LTR and non-LTR families. Non-LTR retrotransposons can be further classified into LINE, SINE, SVA, and retro-genes (processed pseudogenes). Endogenous retrovirus (ERV), L1 and Alu are the main representive subfamilies of LTRs, LINEs, and SINEs. MEs play important in genome evolution and gene functions via variety of mechanisms.
Due to past and ongoing retrotransposition activities, many retrotransposns occurred as insertions uniquely present in the human genomes (human-specific MEs (HS-MEs)) or polymorphic (for their presence and absence) among human individuals (polymorphic MEs). dbRIP serves to provide a comphrehensive documentation of human-specific and polymorphic retrotransposon insertions with detailed sequence characterization and allele frequency (for polymorphic MEs).
dbRIP Track Hub is a composite track consisting the follow specific tracks:
dbRIP tracks are currently available for hg19 and hg38. A more advanced search interface of the data is available at here.
Please refer to the relevant publications listed in the citations.